Pablo Torres Vergara

1.- Disposición de mediadores endógenos y fármacos
2.- Farmacología de receptores nucleares huérfanos y factores de transcripción

1.- Regulation of the ATP-binding cassette transporters ABCB1, ABCG2 and ABCC5 by nuclear receptors in porcine blood-brain barrier endothelial cells.
Ho Yu-Siong, Torres-Vergara Pablo, Penny Jeffrey, British Journal of Pharmacology 2023 Dec;180(23):3092-3109. doi: 10.1111/bph.16196. Epub 2023 Aug 18. PMID: 37476954 (Q1) (Autor correspondiente).

2.- Brain Vascular Dysfunction in Mothers and Their Children Exposed to Preeclampsia.
Escudero C, Kupka E, Ibañez B, Sandoval H, Troncoso F, Wikström AK, López-Espíndola D, Acurio J, Torres-Vergara P, Bergman L.. Hypertension. 2023 Feb;80(2):242-256. (Q1) (Co-autor).

3.- Dysregulation of vascular endothelial growth factor receptor 2 phosphorylation is associated with disruption of the blood-brain barrier and brain endothelial cell apoptosis induced by plasma from women with preeclampsia.
Torres-Vergara P, Troncoso F, Acurio J, Kupka E, Bergman L, Wikström AK, Escudero C.. Biochim Biophys Acta Mol Basis Dis. 2022 Sep 1;1868(9):166451. (Q1) (Autor correspondiente)

4.- How soluble fms-like tyrosine kinase 1 (sFlt-1) could contribute to bloodbrain barrier dysfunction in preeclampsia?
Torres-Vergara P., Rivera R, Escudero C., Frontiers in Physiololgy, Feb 8;12:805082, 2022. (Q1) (Autor correspondiente)

5.- Disruption of the Blood-Brain Barrier by Extracellular Vesicles From Preeclampsia Plasma and Hypoxic Placentae: Attenuation by Magnesium Sulfate.
León J, Acurio J, Bergman L, López J, Wikström A-K, Torres-Vergara P, Troncoso F, Castro FO, Vatish M, Escudero C. Hypertension. 2021, Nov;78(5):1423-1433. (Q1) (Co-autor)

1.- Characterizing the role of the pregnane X receptor and aryl hydrocarbon receptor in the development of neurotoxicity and brain endothelial cell damage. FONDECYT 11230624, Agencia Nacional de Investigación y Desarrollo (ANID), Investigador Principal, 2023.

2.- Saving maternal brains; An international collaboration for increased understanding of brain vascular changes in women with preeclampsia. Proyecto financiado por The Swedish Foundation for International Cooperation in Research and Higher Education (STINT), Co-investigador, 2020.